இன்னொரு புது முயற்சி

இது இன்னிக்கு தான் நடந்தது. எங்க வாத்தியார்க்கு எங்க இருந்து இப்பிடி ஐடியா மழை கொட்டுதோ தெரியலை.

(a) beta-sitosterol, (b) beta-stigmastanol

i could separate them using my CSPs but the problem is Sigma says that the compounds are 99% pure!!

well,that is were the problem is...if it is 99% pure,how can i separate two isomers..so,my prof suggested may be that is not the second isomer!!

:(

PQE என்ற பலப்பரீட்ச்சை!!

kitta thatta 2 vaaraam veetula ellarayum beedhi kilamba vacha ennakku,andha naalum nerungi vandhuchu..April 21,2009 vidiyum podhae,aandavaa endha poludhu romba nalla poludhaa erukanum,yaarum ennai,aenn edhukku nnu kelvikal kaekamaa parthukonnu oru pirarthanaiya saamikitta vachuttu practice session arambichaen.

aethanai murai practice panninaalum andha speech speedai mattum kuraika mudiyala..(genes illa,pinna eppidi maarum,enga appa paesi kaetavangalukku andha unmai puriyum..hehehe.)

eppidiyo oru 2 thadavai practice pannittu kilambitaen. 2:30 PM kku presentation,12:30 manikku venue kku vandhutaen..vandhu ellam sariya erukaannu oru checkinga pottu..marupadiyum rouse vida arambichutaen.

2:30 kku sharp ella examinersum vandhutangaa..umm,arambi unn presentationai appidinnu dhan sonnanga..kada kadannu oppichuttae vandhaenaa..appa nnu parthu ennoda thesis examination committee chairman illa oru kelviya kaettu ennaya stop pannitaar (avarukku namma nilama theriyala pola,stop panna arambikuradhu kastam nguradhu) avar kaeta kelvikku edho thatthu pithu ularittu,avarai partha manushan deep sleep la erukaar..well,adhu sleepa illa thinkingaa nnu avar dhan sollanum.

adhukku apparam naan presentation mudikkura varaikum yaarum kelvi kaekalai..(andha alavukku ellarum deep thinking la erundhu erukanga purinjukonga pa!!)

presentation mudinjadho illayo..aalalukku kelvi kaekuranga..umm,innimae dhan da nammakku aapae nnu ninachu kittu,oru smile oda avangalai face panna thayar agitaen..

Avanga ellarum kaeta kelvigal...ennoda PhD vazhkaila pinnadi thaevai padum appidingura oru napaasai la kurichu vachukuraen!!

(1) explain Inclusion complex-with respect to the hydrophobic behaviour of beta CD.

(2) what other parameters do you change/moniter during your chiral separation?

Mobile phase, particle size, length of the column

(3) what is the advantages of your CSP over other chiral columns available?

cheaper, since it requires very little amount of the CSP particles.

(4) Is it because of your CSP,the separation of the di substituted benzene is better or is it a property of those compounds?

(5) Which compounds can be separated using your CSPs? (ie) which functional group reacts with your CSP--> -NH2, -OH, -COOH etc.

(6)This looks like a totally chemistry research,what has it got to do with faculty of medicine?

(7)According to your thesis title,you ll be doing chiral separation in both drugs and environmental samples. But,there are no results or data showing that you have done any work so far?

(8)

innum oru rendu kelvi kaetanga adhu ennanu theriyamaa mulichittu erukaen,gyanabagam vandhdhum update panniduraen.

edhu pola pala kelvigalai dhinamum vazhkaila sandhichittu dhan erukaen!!

aana,edhulayum oru nalla vishayam enna na--PQE la pass panninadhu dhan.inimae yaaru kaetalum dhairiyamaa sollalaam illa,naan PhD pannuraennu.

-now let us look at the fun side of the so called PQE/Quals:

PQE mudinjadhum pasanga eppidi agiduranga paarungaa?!?!

innum neriya comic strips eduthu vachaen,but endha padhivoda neelathai manasula vachu kittu podalai..

P.S-Tamil la dhan type pannanum nnu erundhaen,enna aachunae theriyala,tamil typing selectionae panna mudiyala!!

எவ்வளவோ பண்ணிட்டோம் இதை பண்ணமாட்டோமா?

இவ்வருட தீபாவளி celebrations (romba kustam pa..tamila type pannuradhu..romba porumai vaenum pola..adhu dhan nammakku suthama kidayadhae) pathi ezhudhanumnu deepavalikku next dayla erundhu yosichukittu erukaen..but sariya naeram kidaikalai. Adhukula ennoru vishayam nada,diwali issue pinnukku thalividapattuladhu(eppodhaikku).

Naethu i started another set of reactions.Edhu ennoru pudhu CSP(Chiral Stationary Phase). I used a new compound--C-Methylcalix[4]resorcinarene. Calix[4]arene oda modified compound dhan but romba different erundhuchu.



The reactions steps are just like that of Calix[4]arene. Dont know how much efficient the reactions would be..but adhukula enn vaathiyaar papers pathi paesa arambichutaar. Endha compound vachi 2 papers publish pannalaam appidinnu..avanga avangalukku oru kavalai..ennakku reactions pogumaannu kavalainaa,edhai vachu aethanai paper anupalaamnu avarukku oru kavalai..

Reactions steps updates will be done later after i get to know the results!!

அவர் பேப்பரைப் பத்தி சொல்லும் போது இது தான் தோண்றியது எனக்கு---எவ்வளவோ பண்ணிட்டோம் இதை பண்ணமாட்டோமா?!!

My worst nightmare AGAIN

I have always wanted to blog, but kept wondering about what to blog. What interesting things could happen in a life of a graduate student. But then after a long DAY, I wanted to ramble about it to someone and that is what is in my VERY FIRST POST here.

Did this have to happen again? I started my synthesis of CSPs after about a couple of months gap (not a vacation guys,just a gap...during which time i had to do analysis) and I really hoped i didnt have anyone peeking and yelling at me from behind..Well,I had all my fingers crossed for that..But it is Murphy's law all over again.

I had planned a day before itself about all those things i ll be doing and yet i messed up things. It all started with the vaccum trap blocked with ice followed by one thing and another. And the stuffs that happened after that is a History!!!

I wasnot allowed to do the reactions myself and When i went forward and said i would love to do it all by myself, i was told that the next time i can do it. Is it not the part of a graduate student's curriculam that he learns the tricks.

I really wish this yelling would stop and i could learn to do some things in my own(!!!) way.

So,now that i have my first post here,I ll make it a point to blog something or other now and then. And i ll make it sure that it is not just ramblings because I do have some great moments to cherish.